Examining The Functional Connectivity Of A Whole Brain Atlas

Background: The brain is often considered the most complex organ in the human body. It is also the most difficult to understand, given the vast array of different functions spread throughout its mass and the interconnected functionality of its regions that makes subdividing it based on form or function a difficult task. Craddock, et al. (2012), in the article examined, attempt to produce a method for further examining the functional connectivity (FC) of the regions of the brain and subdivide them based on spatial positioning and function. Understanding FC in the brain can significantly improve understanding of many brain functions and the effect of outside stimulus of various parts of the brain. This examination will only be able to take place by creating an accurate whole brain atlas. This creation of a whole brain atlas, or a map of the brain separating it into regions of interest (ROI) based positioning and/or function, has typically been done via fMRI analysis of the brain co mbined with an anatomically based mapping procedure. This study seeks to use fMRI technology combined with an algorithm to create voxel clusters or ROI’s that optimize both spatial coherence and homogeneity in regards to the FC of the individual ROIs that can closely match of the results of a voxel-wise analysis, while improving on computation power required and interpretability. Clinical Significance: The usefulness of this technology and methodology can be found in both neurology researchShow MoreRelatedNokias Human Resources System144007 Words   |  577 Pagescollaboration partners and customers; our ability to manage efficiently our manufacturing and logistics, as well as to ensure the quality, safety, security and timely delivery of our products and services; our ability to source sufficient amounts of fully functional quality components, sub ­assemblies and software on a timely basis without interruption and on favorable terms; our ability to manage our inventory and timely adapt our supply to meet changing demands for our products; our ability to successfullyRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesquite an original take on the most extensively covered conflicts in human history and the decades of unprecedented global violence they framed. Morrow’s contribution here, as in his recent research and scholarship as a 6 †¢ INTRODUCTION whole, treats the two wars and their prehistory and aftermaths as genuinely global phenomena, not as conflicts among the great powers of Europe, the United States, and Japan, which has been the obsessive focus of most of the vast literature on this subject